Some people have toothache for a few hours and get better; some people have pain for a few days and get better with some medicine; some people have pain for months and have to go to dentist or stomatologist to have two or three teeth extracted one after another, but the symptoms are not relieved. In this case, patients should go to the neurosurgery department of a regular hospital to further confirm whether they have “trigeminal neuralgia”, which is a painful brain nerve disease, and toothache is one of its typical symptoms. Trigeminal neuralgia is the first pain in the world. Trigeminal neuralgia was once imaginatively called the “first pain in the world”, mainly refers to the recurrent paroxysmal severe pain in the distribution area of the trigeminal nerve on one side of the face, and the pain is usually located in the lips, corners of the mouth, nose, palate The pain is usually located in the lips, corners of the mouth, nose, palate, or oral mucosa. When the condition is severe, the pain can occur all over the face, making people afraid to drink or eat, and even smiling and breathing can cause severe pain. For patients with trigeminal neuralgia, they often feel unbearable pain in the face, and it is always urgent to seek medical treatment. How can trigeminal neuralgia be treated? Clinical studies have found that the trigeminal nerve starts in the midbrain and pontine brain of the human brainstem, and most of its functions are responsible for the sensation of the face, head, and the front two-thirds of the tongue. However, as we age, the blood vessels that travel in the brain become tortuous and displaced, and the thicker blood vessels tighten up against the trigeminal nerve and compress it, causing a disruption in the nerve conduction within the trigeminal nerve, which leads to trigeminal neuralgia. Therefore, the fundamental treatment for trigeminal neuralgia is to remove the blood vessels that are compressing the nerve and insert medical spacers between the blood vessels and the nerve to free the trigeminal nerve from the compression of the blood vessels, and this surgical treatment is called microvascular decompression, which is a minimally invasive procedure to treat trigeminal neuralgia.