Aspiration pneumonia is clinically dominated by Gram-negative bacterial infections, so the antibacterial drugs used for patients with aspiration pneumonia must cover Gram-negative bacteria. For example, three generations of cephalosporins, such as ceftriaxone and ceftazidime, moxifloxacin hydrochloride from the quinolone group and azithromycin from the macrolide group, are all antimicrobial drugs that can be used in the treatment of aspiration pneumonia. Aspiration pneumonia is an inflammation caused by reflux of material from the gastroesophagus into the lungs. Patients usually present with choking cough, fever, sometimes high fever accompanied by cough, coughing up pus, and wet rales can be heard in the lungs. It is mainly seen in patients who are bedridden for a long time, such as patients with cerebral hemorrhage, cerebral infarction or those who have traumatic brain injury, and who have impaired swallowing function. The main treatment for aspiration pneumonia is early anti-infection with antibacterial drugs and, if necessary, fibrinoscopic aspiration.