The cause of the disease is not very clear, but it is related to the long-term stimulation of estrogen. Modern medicine believes that the occurrence of uterine fibroids is related to estradiol, and domestic data show that 0.4%-0.8% of uterine fibroids have the possibility of sarcomatous transformation. If the fibroids increase rapidly within a short period of time or with irregular vaginal bleeding, sarcoma should be considered as a possibility. If the fibroids increase in postmenopausal women, they should be alerted to the possibility of malignancy. The cause of uterine fibroids is the high amount of estrogen receptors in the fibroid tissue, or the higher sensitivity of the receptors compared to normal uterine muscle tissue, or the proliferation of smooth muscle cells in the uterine wall due to the high level of estrogen in the body over a long period of time, resulting in the overgrowth of fibroids. There is also a neurocentric, cytogenetic relationship. In clinical practice, fibroids rarely occur before puberty, and the phenomenon that fibroids grow with pregnancy and shrink with menopause confirms that estrogen is the main promoter of fibroid growth. For the question of how to treat fibroids, there are many treatment methods available to women, such as medication, surgery, and minimally invasive treatment. In order not to remove the uterus and to preserve the integrity of female anatomy and physiology to the maximum extent. It is recommended to use first-class minimally invasive hysteroscopy and laparoscopy for treatment, striving to minimize the damage to women’s treatment.