Cephalosporins refer to cephalosporin antibiotics, which are widely used as clinical antibiotics, cephalosporin preparations include a variety of drugs, in accordance with the characteristics of its antibacterial effect, the clinical cephalosporins are divided into five generations, as follows. 1. The first generation of cephalosporins: mainly used for the treatment of Gram-positive globular bacterial infections, the representative drugs are cefazolin, cephradine and so on. 2. Second-generation cephalosporins: its antibacterial spectrum is broader, mainly used for the prevention of surgical infections, representative drugs are cefuroxime, cefotiam, cefmetazole, cefoxitin, etc.. 3. Third-generation cephalosporins: mainly used in the treatment of gram-positive bacillus infections, the representative drugs are cefotaxime, cefodizime, ceftriaxone and so on. 4. Fourth-generation cephalosporins: its antibacterial effect on drug-resistant bacteria to enhance the clinical use of severe bacterial infections, the representative drugs are mainly cefpirome, cefozonan and so on. 5. Fifth-generation cephalosporins: such as cephalosporin (ceftaroline), cefeprime (ceftobiprole) and so on. It should be noted that cephalosporin antibiotics are prescription drugs, the specific use should also be under the guidance of the physician to follow medical advice.