The treatment drugs for cirrhosis with ascites include drugs for treating primary disease, diuretics, human albumin, vasoconstrictive active drugs, anti-infective drugs and other symptomatic supportive drugs. 1. Drugs for treating primary disease: such as antiviral treatment for viral hepatitis; targeted drugs, intervention, radiotherapy, surgery and other treatments for hepatocellular carcinoma. 2. Diuretics: furosemide, spironolactone, etc. are commonly used; tolvaptan and other diuretics should be applied when necessary for persistent ascites. 3. Human albumin: elevate the level of blood albumin to reduce ascites. 4. Vasoconstrictive active drugs: such as terlipressin, usually used in conjunction with human albumin to prevent circulatory dysfunction after ascites release. 5. Anti-infective drugs: If ascites is combined with infection, anti-infective treatment should be carried out, commonly used rifaximin and so on. 6. Other symptomatic supportive drugs: such as lactulose to reduce blood ammonia, prevention and treatment of constipation; Mentholatum ornithine and other treatment of hyperammonia. Cirrhosis with ascites is recommended to consult the doctor in time, improve the relevant examination to clarify the cause of the disease, and then carry out standardized treatment to avoid delaying the condition.