Is interventional treatment for uterine fibroids safe?

  Uterine fibroids are the most common benign tumors of the female reproductive system, with an incidence of 20-25% in women over 35 years of age. Clinical symptoms include excessive menstruation, anemia, and a feeling of lower abdominal cramping. Large tumors can lead to frequent urination and difficulty in defecation, fever and increased leucorrhea and odor in cases of co-infection, and can lead to infertility in severe cases. Asymptomatic cases can reach 37%. Interventional techniques are used to treat uterine fibroids with good results. By blocking the blood supply to the fibroids, the fibroids become necrotic and shrink, with an efficiency of 96% and a low recurrence rate.  Compared with conventional gynecological surgery, interventional treatment of uterine fibroids has the following advantages: (1) the use of arterial cannula for drug injection, which is less invasive; (2) avoiding the removal of the uterus, preserving the reproductive function and female secondary sexual characteristics; (3) fewer complications and faster recovery of patients.  The safety of interventional therapy has been studied from the following aspects: 1. Clinical studies: including operation time and treatment effect. The operation time is closely related to radiation safety. Skilled interventional operation technique is the key to shorten the operation time and improve the safety of interventional treatment. We have a team with rich experience in interventional treatment and skillful operation skills, which is the fundamental guarantee to improve the safety of surgery and reduce the occurrence of intraoperative hazard rate.  2. Pathological study: including pathological changes of the uterus, ovaries and fallopian tubes after embolization. We have adopted pathological changes as the gold standard to explore the changes of organ tissues after interventional treatment and to confirm the safety of interventional treatment from the pathological point of view.  3. Angiological study: It mainly includes the establishment of uterine collateral circulation after interventional treatment, indicating that embolization of uterine arteries does not cause severe ischemia in the normal myometrium of the uterus.  4.Reproductive endocrinology study: It includes the effect of interventional treatment on ovarian endocrine function and reproductive function of patients. As long as the appropriate embolic agents are applied to avoid excessive embolization of ovarian branches and ovarian tissues, the damage to ovarian function by interventional therapy can be prevented and has no effect on reproductive function.  5. Radiation protection and other studies: including monitoring and evaluation of the amount of X-ray radiation received by the patient and the operator during the procedure. The amount of X-ray radiation received by the interventionalist and the patient during interventional treatment is within the normal tolerable range. As long as the radiation protection of the patient and the interventionalist is strengthened, interventional treatment is a safe treatment method.