Most intracranial infections can be cured. For example, viral intracranial infections are cured when the pathogens in the cerebrospinal fluid are killed by giving sufficient amount and course of antiviral drugs. Some patients may have serious brain tissue damage after intracranial infections, and after the pathogens are killed, i.e., after the cure, they may still have recurrent seizures or reduced intelligence, such as dementia, or limb paralysis, which is not untreated. As long as the pathogenic bacteria in the brain are killed and the full course of treatment is completed, the disease is cured, but because of the more serious damage to brain tissue or a longer course of disease, it may leave sequelae. There is also a special kind of intracranial infection, namely HIV infection, which can also reach the brain tissue after long-term infection, but HIV itself is an incurable disease, so if the intracranial infection is caused by HIV, the treatment effect may not be good.