Patients with fungal infections of the external auditory canal who have no contraindications to povidone-iodine can use povidone-iodine for topical disinfection. However, povidone iodine can only be used for disinfection, can not treat the purpose of fungal disease, but also need to follow the doctor’s instructions to take antifungal drug treatment. Povidone-iodine can be used to disinfect the skin and mucous membranes, povidone-iodine is a topical drug, and oral administration is contraindicated. For fungal infections of the external auditory canal, povidone-iodine alone can not play a role in the treatment of the disease. If the patient with fungal infection of the external auditory canal is combined with bacterial infection, iodophor can be used for local disinfection. Once diagnosed with fungal infection of the external auditory canal, patients can use topical antifungal drugs, such as clotrimazole, etc., under the guidance of the doctor, and oral antifungal drugs, such as mycotoxin, etc., can be added to the treatment of severe symptoms. Patients with fungal infections of the external auditory canal need to follow the doctor’s instructions during the treatment period, regular review, in order to understand the recovery of the disease.