1, sexual transmission route; 2, close contact; 3, indirect contact: through contact with the infected person’s clothing, household items, utensils, etc.; 4, medical source of infection: medical personnel in the treatment and care of poor protection, resulting in their own infection or through medical personnel to patients; 5, mother-to-child transmission: is by the infant through the maternal birth canal of close contact. 6, smoking can increase the effect of HPV infection