Clinical information of patients with cutaneous tuberculosis to improve the understanding and treatment of cutaneous tuberculosis. Patients had an insidious onset, patients had a past history of tuberculosis, and patients were combined with pulmonary tuberculosis or with regional lymph node enlargement. The clinical manifestations are a variety of non-characteristic skin lesions, and the combination of pathology such as infiltration of epithelioid cells and lymphocytes to form tuberculous nodules and caseous necrosis helps in the diagnosis. Patients with cutaneous tuberculosis have a better prognosis with standardized treatment. Conclusion Skin tuberculosis has diverse manifestations and is easily misdiagnosed, which should be taken seriously by clinicians. Antacid bacillus examination, pure protein derivatives test, and histopathological examination of suspected patients can help in diagnosis. Cutaneous tuberculosis is skin damage secondary to tuberculosis lesions of the skin or other organs of patients with cutaneous tuberculosis by Mycobacterium tuberculosis, from 18 to 68 years of age, with a mean of (41.3±10.2) years. Typical lesions include applesauce-like lupus nodules (brownish yellow like applesauce on slide indentation), which are caused by the immunity of the organism, the amount of Mycobacterium tuberculosis, toxicity and invasion of the disease for 2 months to 5 years, with different pathways and a variety of clinical manifestations, and nodules with early typical “three contours” symptoms (central reticular scar, wart-like margin, surrounding redness). The clinical manifestations are atypical and easily misdiagnosed. In order to improve the diagnosis and treatment of cutaneous tuberculosis, the onset of the disease is insidious, with local pain and pruritus, or no obvious self-conscious symptoms.