Five times the seeds can be used to treat premature ejaculation caused by the lack of solidity of kidney qi. Premature ejaculation in Chinese medicine can be divided into the liver meridian damp-heat syndrome, heart and spleen deficiency syndrome, phase fire paranoia syndrome, kidney qi is not solid evidence, five times the seeds have the effect of fixing spermatozoa and stop the spermatorrhea, so it can be used to treat premature ejaculation due to kidney qi is not solid. With sour, astringent, cold nature, Wu Bei Zi has the effect of astringent (astringent lung qi) to reduce fire, astringent to stop diarrhea (by enhancing the astringent function of intestines to relieve diarrhea), fixing spermatozoa to stop emission and stopping bleeding, etc. It has therapeutic effect on the cases of prolonged cough with lung deficiency, phlegmatic cough with lung heat, prolonged diarrhea and dysentery, spermatozoa emission, spermatogenesis, metrorrhagia, blood in stool and so on. It should be noted that damp-heat diarrhea (diarrhea caused by feeling damp-heat evil) should not be used. Therefore, five times the seeds for premature ejaculation belongs to the kidney qi is not solid evidence of a certain therapeutic effect. Premature ejaculation patients should consult a doctor to guide the use of medication, not blindly self-medication.