Moles are usually treated with strong acid or alkali drugs, which can be irritating and corrosive to the skin, so it is usually not recommended to remove moles with medicated water. Because of the slow action of medicine to remove moles, irritation and corrosion of human skin, and may cause deep scarring, the current clinic does not use medicine to remove moles, common mole removal including laser mole removal, surgical excision and so on. Laser mole removal technology is based on the selective photothermal effect of laser, its high-intensity radiation energy focused on melanin, mole pigment tissue particles, will be directly vaporized, broken, so as to achieve the purpose of removing the effect can generally be maintained for a long time. Surgical excision is applicable to sebaceous moles after puberty and pigmented moles occurring in friction-prone areas such as groin, palms and soles of feet, etc. It is performed by anesthetizing the area around the moles so as to excise them, and the edges of the healthy skin are also excised if necessary. Mole removal should be done in a professional and regular hospital for consultation and treatment, and should not be done blindly by using mole removal potions on one’s own, as this may cause allergic and other skin reactions and damage to the skin.