High jaundice in children refers to high levels of bilirubin in children, which in turn causes jaundice. Jaundice in children can be divided into physiological jaundice and pathological jaundice, physiological jaundice occurs in newborns, no special treatment is needed, in most cases can subside on its own within 1 week. Pathological jaundice in children has more causes and usually requires therapeutic measures according to the following causes: 1. Neonatal hemolytic disease: Immune hemolysis caused by incompatibility between maternal and child blood group antigens, jaundice is one of the typical symptoms, mostly appearing within a few days after birth. Can be treated by intravenous injection of gammaglobulin, as well as light therapy, in serious cases require blood exchange, jaundice can subside after the original disease is cured; 2, breast milk jaundice: breast-fed children, jaundice within 1 week after eating breast milk, may be breast milk jaundice, and breast milk composition, the child’s liver is not mature, breastfeeding can be suspended for a few days, some children jaundice can gradually subside, if jaundice If jaundice continues to be unrelieved, light therapy can be carried out; 3, jaundice hepatitis: mostly caused by viral infection of the liver inflammation, which can cause jaundice, fatigue, nausea and vomiting in children, treatment can use cholagogic drugs, supplemented by liver cell membrane stabilizers and other hepatoprotective drugs for treatment, after the hepatitis is controlled, jaundice will also gradually subside; 4, neonatal sepsis: due to pathogenic infections resulting in systemic inflammatory disease, in addition to jaundice, may also appear fever, drowsiness, hypermobility and other symptoms, can be treated with antibacterial drugs such as penicillin and erythromycin, supplemented by immunoglobulin to achieve the purpose of subsiding jaundice; 5, congenital biliary atresia: is a congenital bile duct obstructive disease, may be related to developmental malformations or viral infections. This disease presents with jaundice that is progressive in nature and requires surgical treatment. In addition to the common diseases mentioned above, congenital pyloric hypertrophy, megacolon, erythrocyte enzyme defects, and hemoglobinopathies can cause the development of jaundice in children. Therefore, if the jaundice is severe and does not subside for a long period of time, it is recommended to seek prompt medical attention to identify the cause and to treat it actively.