The causes of hand numbness and face numbness are mainly seen in brain diseases, cervical disc herniation, peripheral neuropathy, etc. The details are as follows: 1. Brain diseases: if it is persistent numbness on one side of the face and numbness in the hands, this is the time to do a cranial MRI to understand whether there is acute cerebrovascular disease or there is demyelinating disease, such as multiple sclerosis; 2. Cervical disc herniation: if it is paroxysmal and Lasting for a short time, ask the patient if there is any sleep disorder, whether it is easy to appear at night or during the day, and need to do cervical MRI to understand if there is cervical disc herniation; 3, peripheral neuropathy: ask the patient if there is any long-term use of certain drugs, or exposure to toxic substances, such as lead, mercury, such substances poisoning caused by peripheral neuropathy, appearing face numbness, hand numbness.