Most of these reactions are due to the toxicity of the protein antigenic microorganisms contained in the vaccine, and generally do not require treatment and can return to normal in 1-2 days. In addition, patients who are immunocompromised, immunocompromised or have allergies can have more serious abnormal reactions after vaccination. The most common abnormal reaction is anaphylaxis. Therefore, in order to prevent anaphylactic shock from occurring in Fang Sheng, before injecting tetanus antitoxin, the patient should be asked if there is any history of allergy, while the corresponding intradermal test injection should be given, and the corresponding rescue drugs should be prepared to prevent anaphylactic shock.