Perilla leaf belongs to a kind of traditional Chinese medicine, with the efficacy of dispersing cold and relieving symptoms, moving Qi and resolving phlegm, and calming the fetus, etc. It is often used clinically to treat wind-cold and cold, spleen and stomach stagnation, chest congestion and vomiting, fetal disturbance, and poisoning from eating fish and crab. The toxic side effects of perilla leaves are usually small, and can be seen in the following: 1, allergy: perilla leaves are irritating and may lead to allergic reactions in patients with allergies; 2, damage to internal hematopoietic capacity: excessive consumption may lead to damage to the human nervous system and digestive system, and in severe cases may also damage the internal hematopoietic capacity. The contraindications of perilla leaf usually include the following aspects: 1, the combination of contraindications: perilla leaf with anesthetics, sedative drugs, may prolong the effect of drugs, when combined with the need to pay attention to reduce the dose; 2, dietary contraindications: consumption of perilla leaf during the consumption of cold, stimulating food, so as not to affect the therapeutic effect of drugs; 3, contraindicated people: allergic patients caution consumption; for Yin deficiency, Qi deficiency and warm disease The consumption of perilla leaves may lead to deficiency of both qi and yin, so such patients should also avoid or be cautious about consumption.