Genital warts, also known as condyloma acuminata or venereal warts, are a type of proliferative genital perianal damage caused by the human papilloma virus (HPV). It occurs mostly in young people between the ages of 18 and 35. The disease is mainly transmitted through sexual contact, but can also be transmitted vertically and through indirect contact. The incubation period of the disease is 1 to 8 months, with an average of 3 months, and it mainly occurs in sexually active people, with a predilection for young people aged 18 to 35 years, accounting for more than 80%. The external genitalia and the perineum are the most frequent sites of the disease. Vaginitis in women and male circumcision are auxiliary factors for the occurrence and growth of the disease. In males, it is more common in the coronal sulcus, glans, prepuce, tether, penile body, perineum and scrotum, while in females, it is more common in the labia majora and minora, posterior union, vestibule, cervix and perineum. Occasional lesions may occur outside the vulva and perianal area, usually in the axilla, umbilicus, oral cavity, breasts, and between the toes. The lesions start out as small, reddish papules, which gradually increase in size and have an uneven, rough surface, usually without any special sensation, and then gradually proliferate and spread outward. The surface of the warts is often moist, white, red or dirty gray. The wart may occasionally feel like a foreign body, itchy and painful during intercourse, and may break down, bleed, ooze or become infected. The actual treatment of genital warts is to pay attention to the combination of other STDs or local infections, if there is a simultaneous treatment, otherwise the efficacy is poor and the recurrence rate is high. The actual HPV is a subclinical infection that should be treated as soon as possible by doing 5% acetic acid test or further biopsy pathology, and PCR test or HC2 test if conditions permit. Sexual partners should be treated at the same time and should not have sex until cured. Most sexual partners may already have subclinical infection with HPV. Even if there are no obvious warts, regular follow-up examinations are necessary. Ancillary tests such as 5% acetic acid and HC-2 may be used. If regular review is not guaranteed, topical medications such as imiquimod and interferon may be used for control. Prognosis and regression Treatment usually results in a wart-free state, but many patients will still have virus lingering in the epithelial cells. The recurrence rate of warts is more than 40%, and the absence of recurrence for 6 months is considered as “clinical cure”. The most important thing is that you can get a good idea of what you want to do. In a few cases, vulvar or cervical cancer may occur.