Psoriasis refers to psoriasis, which is an immune-mediated, chronic, relapsing, inflammatory, systemic disease induced by a combination of genetic and environmental effects. Flumethasone ointment is a glucocorticoid, and retinoic acid cream is a retinoid, both of which can treat psoriasis, so flumethasone ointment is effective in combination with retinoic acid cream for the treatment of psoriasis. Flumethasone ointment is suitable for non-infectious inflammatory skin diseases that are effective for corticosteroid treatment, especially those related to hyperkeratosis, such as psoriasis vulgaris. However, attention should be paid to its adverse effects, large-scale long-term application of glucocorticoids can cause systemic adverse effects, sudden discontinuation of the drug can induce pustular or erythrodermic psoriasis. Vitamin A cream can be used for keratosis pilaris. Adverse reactions are erythema, swelling, flaking, crusting, increased or decreased pigmentation may occur at the site of application. So the combination of flumethasone ointment and retinoic acid cream is effective in the treatment of psoriasis, but it needs to be used under the supervision of a doctor. Psoriasis patients are advised to go to the dermatology department of the hospital in a timely manner, under the guidance of the doctor’s medication, do not use medication without authorization.