HPV type 52 infection is clinically classified as a high-risk HPV infection. About 80% of patients will turn negative on their own after about 1 year, so regular review should be given. 20% of infected patients will have persistent infection, and persistent infection will lead to lesions of the cervical epithelium. In the case of cervical epithelium under persistent high-risk HPV infection, low grade lesions will occur in about 2-3 years, which will then transform to high grade lesions and then to cervical cancer. Once a high-risk HPV infection is detected, it is difficult to determine the timing of high-risk HPV infection because it is not a frequent medical checkup. Colposcopy is recommended as soon as possible, mainly to find out if there are epithelial lesions in the cervix. If the colposcopy result is negative, screening for cervical cancer is recommended once every year.