Running is a kind of anaerobic exercise, if running for a long time may cause an increase in the oxygen demand of the human body, which may relatively cause cerebral hypoxia. Running for a long time may cause more sweating, which may easily cause hypovolemia, and hypovolemia may cause hypoperfusion of the brain, which may easily cause insufficient blood supply to the brain also may cause hypoxia to the brain. Running may cause a faster heartbeat, which may easily cause the heart to pump less blood, which may also cause low perfusion in the brain, which may cause ischemia and hypoxia in the brain. In severe hypoxia patients may experience headache, dizziness, nausea, vomiting, etc. It is important to replenish the blood volume in time after running and to give oxygen therapy if necessary. If patients have serious headache and dizziness symptoms, they should be given treatment to improve blood circulation as well as improve brain metabolism.