Facial cyanosis, medically called nevus of Ota, is a kind of birthmark, most of them are present at birth or soon after birth, some of them occur several years or even more than ten years after birth, and a few of them develop even later, so the people call it cyanosis. The cause of this disease is unknown. The lesions are pale cyan, gray-basket, brown-blue to blue-black or yellow-brown patches or dense spots, and the edges of the patches often fade. The spots are distributed in clusters, varying in sparseness, or with central patches and marginal spots. The most common sites of involvement are the periorbital area, frontal area, forehead, zygomatic area, temporal area, and nasal flanks, with unilateral distribution and occasionally bilateral. About two-thirds of patients have ipsilateral scleral blue staining. The color of nevus of Ota can vary, such as darker in summer and lighter in winter, and emotion also has an effect on the color. The clinical manifestation of nevus of Ota varies greatly. In light cases, it can only be a light brown dotted or flaky pigmented spot around the eye orbit, while in heavy cases, it can be a brown, greenish-brown or greenish-black pigmented spot on the unilateral face or both sides. Linlin Xin, Department of Dermatology, Shandong Qianfo Mountain Hospital For nevus of Ota, the effect of laser treatment has been very positive. Mostly Q-switched Nd-YAG 1064nm laser or 755nm emerald laser is used, and 694nm ruby laser can also be used. Usually, 3 to 6 treatments are given every 1 to 3 months, and eventually a complete cure can be obtained. During laser treatment, surface anesthetics are applied locally, which is less painful and generally tolerated. After treatment, there will be varying degrees of skin edema and skin bleeding in the treated area, which usually crusts over and fades in about a week, and usually leaves no marks after fading. For children, they are too young to cooperate well during and after surgery, and need to be treated with general anesthesia. If conditions are available, early treatment is possible, and nevus of Ota is not good for the psychological health growth of young children and can easily affect their psychological health.