Keratosis pilaris should be treated first by treating the thickened stratum corneum and then topical antifungal medication. Keratosis pilaris has two causes, the first is in the infection of fungi at the same time, long-term friction caused by keratosis pilaris; the second is long-term repeated fungal infection stimulation caused by keratosis pilaris. The most effective way of treatment is still topical antifungal treatment, to achieve the therapeutic effect should first deal with the stratum corneum, it is recommended that each time before the use of medication to use hot water to soak, soften the stratum corneum, and then remove the stratum corneum and then externally coated with antifungal medication, coated with drugs should be repeatedly massaged so that the drug uniformly and effectively penetrate into the skin. Commonly used topical drugs are terbinafine cream, clotrimazole ointment and so on. You can also use topical salicylic acid ointment to remove keratinization first, and then apply antifungal drugs at the same time. If the keratinization is more serious and the fungal infection has reached the deep part, it is recommended to take oral antifungal drugs, commonly used oral antifungal drugs include itraconazole capsule, terbinafine capsule and so on. The use of the above drugs should follow the doctor’s instructions. It is recommended that patients go to the hospital in time, under the guidance of the doctor to standardize the treatment.