Under normal circumstances male sexual life from penile erection, penetration to the end of ejaculation, the whole process, depending on age, physical condition varies greatly. Generally speaking, it is slightly shorter in youth, and most people gradually lengthen it as they grow older and become less sexually excited and more sexually experienced. Some information shows that the general healthy middle-aged people about 2~5 minutes. Clinically, for the convenience of research, we call the time period from penile insertion into the vagina to ejaculation the ejaculatory latency period. Many studies have shown that most normal men have an ejaculatory latency period ranging from 2 to 30 minutes, with the majority of men in the 5 to 10 minute time period. If it is less than 2 minutes, it belongs to the category of premature ejaculation, more than 30 minutes ejaculation, called ejaculation difficulties, if it is greater than 30 minutes, still can not ejaculate, called ejaculation disorder. I. Psychological factors: For most young people, especially those who have just started to have sex, they are mostly related to psychological factors. 1, when you first start to have sex, especially the first time sex, because of the strong sexual excitement, especially vigilant about their sexual ability, expect high quality to complete sex life, with inexplicable anxiety, which affects the performance of sex life. This kind of anxiety will become more and more serious because of the unsatisfactory performance of sexual life. Some patients can appear to be afraid of the female partner, want to have sex but are afraid of sex, very depressed in front of their spouse, and even trembling, afraid of losing each other’s love. This anxiety will inevitably lead to disorders of sexual nerve function. 2, teenage time filled with guilt masturbation. The actual masturbation itself is not terrible, the terrible resulting bad psychological pressure. The actual fact is that you can find a lot of people who are afraid of being discovered and have to finish their ejaculation in a fast state. This constant reinforcement of early ejaculation will become a kind of abnormal “excitement foci” that will stimulate ejaculation and promote premature ejaculation in the future during sexual life. The actual fact is that you will be able to get a lot more than just a couple of hours to get a lot more than just a couple of hours. The actual fact is that you can find a lot of people who are not interested in the actuality that you’re not. Premature ejaculation and even erectile dysfunction are bound to occur in the long run. 4, the misunderstanding of premature ejaculation, that can not cause the female orgasm is premature ejaculation, or male to compare with each other (the common problem of the country, always like to brag about how thick, how hard, how long lasting, in fact, no other blowing so cow!) The fact is that the problem is not as bad as the other person’s. This increases the psychological burden and makes it easier for problems to arise. 5, the factors of sexual behavior: the speed of ejaculation and sexual position, penis pumping amplitude, frequency is closely related, but also with the cooperation of women. If the woman intends to contract the vagina and increase the tight grip on the penis, the male stimulus is strengthened and ejaculation is promoted. Therefore, close cooperation between the couple, long-term cooperation and continuous accumulation of experience, to improve the quality of sexual life has a vital role. Second, pathological factors 1, neurological diseases: brain disease (brain injury, epilepsy, etc.), cremaster disease (tumor, trauma), peripheral neuritis, etc. can lead to premature ejaculation when it affects the higher and lower centers of ejaculation. 2, genitourinary system diseases: glansitis, prostatitis (this disease is closely related to premature ejaculation), vesiculitis, seminal vesiculitis, due to the stimulation of inflammation, increased sexual sensitivity, can cause premature ejaculation. In addition, the foreskin system is too short can also cause premature ejaculation. 3, the penis is too sensitive: this is the hot spot of research in recent years. It was found that the somatosensory evoked potential latency caused by penile head stimulation in premature ejaculation patients is shortened, and the sensory threshold of the penis is reduced with increased nerve excitability. Therefore, reducing sensitivity by topical drugs or changing the concentration of some neurotransmitters in the brain (5HT) by oral drugs can prolong the ejaculation time and treat the effects of premature ejaculation.