The treatment options for patients with middle and late stage cardia cancer are as follows: 1. Comprehensive treatment mainly based on surgery: if the patient has no obstacle in eating, preoperative neoadjuvant treatment, including preoperative radiotherapy and preoperative chemotherapy, can be carried out to control the tumor and make it shrink to within the resectable range of surgery, and then carry out surgery, under the premise of ensuring their adequate nutrition. 2.