The difference between flat warts into spots and age spots mainly lies in the pathological mechanism, etiology, symptoms and other aspects. 1. Pathological mechanism: flat warts into the spot is caused by pigmentation, while the age spot is a kind of epidermal benign tumor. 2. Etiology: flat warts into the spot is mainly human papillomavirus infection, the formation of flat warts after the subsidence of local pigmentation caused by, and the age spots, also known as seborrheic keratosis, is mainly due to skin aging, genetic mutation. 3. Symptoms: flat warts into the spot is mainly manifested as light brown patches, usually no obvious symptoms, while the age spots are mainly dark, rough surface, clear boundary, the size of the spot, usually no obvious symptoms, a few skin lesions may appear itching or pain. It is suggested that patients should seek medical treatment in time to clarify the specific type of disease under professional doctor’s examination and receive targeted treatment in time.