Panic in the middle of the night can not sleep and vagus nerve reflex, neurasthenia, nighttime hypoglycemia and other factors. 1. Vagal reflex, at night, people vagus nerve excitation, easy to induce heart rate acceleration, causing panic and other discomforts, relaxation, adjust the sleeping position can mostly be relieved. In addition, some tachyarrhythmic diseases, such as paroxysmal supraventricular tachycardia, paroxysmal atrial fibrillation, etc., may also be triggered by vagal excitation at night, most of these have a past history of disease, the need to adjust the medication. 2. Neurasthenia, autonomic disorders, may cause panic, difficult to sleep and other conditions, may also be accompanied by irritability, dizziness and other discomforts, this situation requires medical examination and treatment. 3. Nocturnal hypoglycemia, less sugar intake during the day, or taking hypoglycemic drugs at night, easy to transient nocturnal hypoglycemia. In addition to panic, this condition may be accompanied by sweating, hand shaking, hunger and other discomforts, especially the elderly diabetic patients are more likely to be induced. It is usually quickly relieved by lying down and replenishing sugar properly. In either case, prompt medical attention is required the next day to adjust the neurological and endocrine functions, as well as the application of hypoglycemic drugs under the guidance of a physician.