Topical application of quinquefoil is not effective in treating premature ejaculation. Premature ejaculation can be treated with medication, behavioral therapy, psychotherapy and other methods. It is a kind of traditional Chinese medicine, has the effect of astringent lung (astringent lung qi) to reduce the fire, astringent stop bleeding (with the astringent effect of the drug to treat bleeding disease), solid semen stopping (consolidation of semen, prevention and treatment of spermatorrhea), and astringent dampness astringent sore and so on. There is no scientific basis for the treatment of premature ejaculation with the external use of five times the seeds, can not be used for the treatment of premature ejaculation. The treatment of premature ejaculation includes medication, behavioral therapy, psychotherapy and so on. 1. medication: patients with premature ejaculation can take oral medication to delay ejaculation time, such as dapoxetine, citalopram, fluoxetine and so on. Can also be used externally to reduce the sensitivity of the penis and glans, commonly used drugs are compound lidocaine cream, dacronine hydrochloride, and so on. 2. Behavioral therapy: patients with premature ejaculation can also be relieved by behavioral therapy, commonly used methods are extrusion method and dynamic stopping therapy. Mainly through the penis squeeze and behavioral control to reduce penile sensitivity, thus delaying the time of ejaculation. 3. Psychotherapy: Psychotherapy is mainly through the regulation of the patient’s nervousness, anxiety, depression and other negative emotions, through emotional relief to improve the patient’s premature ejaculation. If there is premature ejaculation, it is recommended that the patient go to the hospital in time for relevant examinations to identify the cause of the disease and then carry out targeted treatment. If you need to use drugs, it is recommended to use them under the guidance of a professional doctor.