Skin and soft tissue infections Skin and soft tissue infections include folliculitis, boils, carbuncles, lymphangitis, acute cellulitis, burn wound infections, post-surgical incision infections, and decubitus ulcer infections. Folliculitis, boils, carbuncles and wound infections are most commonly caused by Staphylococcus aureus; lymphangitis and acute cellulitis are mainly caused by Streptococcus pyogenes; decubitus infections are often a mixture of aerobic and anaerobic bacteria. Skin and soft tissue infections with extensive foci and systemic symptoms such as fever or comorbidities are complex skin and soft tissue infections; those without the above conditions are simple skin and soft tissue infections. Treatment 1, skin, soft tissue infections in small and superficial lesions, the number of small, such as pustulosis, only need local medication. When the lesions are extensive and accompanied by systemic symptoms such as fever, it is appropriate to apply antibacterial drugs systemically at the same time. Patients with mild infections can be administered orally, while patients with severe infections can be administered intravenously. 2. Local medication is mainly antiseptic and antiseptic agents (such as iodophor), and in a few cases, certain antibacterial drugs mainly for local application, such as mupirocin, can also be used. 3. Empirical treatment can be given for common pathogens in mild cases. In patients with significant signs of systemic infection, traumatic pus culture should be done, and blood culture should be done at the same time, and drug sensitivity test should be conducted after the pathogenic bacteria are known, and medication should be adjusted accordingly if necessary. 4. When there is abscess formation, timely incision and drainage should be performed. Principles of treatment 1. Conduct pathogenic microorganism examination and drug sensitivity test of blood and pus as soon as possible. 2.Infer the possible pathogenic bacteria according to the source of infection and clinical manifestation, and start the empirical treatment of antibacterial drugs immediately. 3. Combined application of anti aerobic and anti anaerobic drugs. Initial treatment should be given intravenously; after the condition improves significantly, it can be changed to intramuscular injection or oral administration. 4.After obtaining the results of pathogenic bacteria and drug sensitivity test, adjust the medication combined with the effect of empirical treatment. 5. Timely drainage of pus and local treatment should be given after infection control.