Flat warts is a benign superfluous organism caused by human papilloma virus infection of the skin mucous membrane, clinical mainly according to the patient’s specific condition, the use of topical drugs, intradermal injection, physical and other methods of reasonable treatment, there is no best treatment method. 1. Topical drugs: Topical drug therapy is not suitable for patients with physical therapy, according to the different conditions of the choice of topical drugs and methods of use. Commonly used drugs include: retinoic acid ointment, 5% imiquimod ointment and so on. 2. Intra-lesion injection: Vitamin D3 can be injected into the lesion to achieve the purpose of treatment, which is mainly applicable to patients with multiple lesions; Bleomycin intra-lesion injection can promote necrosis of flat warts lesions, form a crust and then fall off to achieve the purpose of treatment. 3. Physical therapy: Physical therapy freezing, electrocautery, scraping and laser are effective treatment methods, the number of lesions can be divided into batches and times of treatment. The best way to treat flat warts is not to have the best treatment method. It is recommended that the patient should consult the doctor in time, under the guidance of the professional doctor, to avoid blindly using medication on their own.