Dengue fever is an acute insect-borne infectious disease caused by mosquito-borne transmission of dengue virus. Clinical manifestations include high fever, headache, severe muscle and bone and joint pain, skin rash, bleeding tendency, swollen lymph nodes, reduced white blood cell count, and thrombocytopenia. It is one of the leading causes of death among children in Southeast Asia. The name “Dengue” is derived from the English Dengue, and the origin of Dengue varies; the more common theory is that it comes from the Swahili word “Ki-dingapepo”, which means It means “sudden cramps, as if haunted by a demon”. In Taiwan, it is known as dengue fever, tengu fever, or bone-breaking fever, while in mainland China it is called dengue fever, and in Singapore and Malaysia it is called bone pain fever or mosquito fever. In Vietnam, it is commonly known as febrile hemorrhagic fever. The preliminary symptoms of dengue fever are similar to cold, so many patients treat it as cold, which not only delays the time but also aggravates the disease. Dengue fever is clinically classified into mild, typical and heavy. Light dengue fever is not terrible, but heavy dengue fever is a horrible killer, with a death rate of more than 90%. The first symptom of dengue fever is fever, which usually starts rapidly with fever, headache, accompanied by back, bone, muscle and joint pain, nausea, vomiting, abdominal pain, diarrhea and constipation, etc. The rash, flushing of the face, conjunctival congestion and superficial lymph node enlargement start to appear in 3~5 days. Early dengue fever patients have very sore muscles all over the body and the slightest touch can cause great pain. If early dengue fever is not effectively controlled, bleeding symptoms of varying degrees of severity may occur. Severe dengue fever may be suddenly aggravated on the basis of the above manifestations with signs such as meningitis and central respiratory failure hemorrhagic shock. Clinical manifestations of dengue fever The incubation period is from 2 to 15 days, with an average of about 6 days. 1.Dengue fever (1)The onset of fever is mostly sudden, the body temperature reaches more than 39℃ rapidly, usually lasts for 2-7 days, the fever pattern is irregular, some cases have their body temperature drop to normal on the 3rd to 5th day, and then rise again after 1 day, showing a bimodal fever pattern. In children, the onset of the disease is slower and the fever level is lower. The onset of the disease is accompanied by headache, back pain, muscle and joint pain, orbital pain, retro-ocular pain and other systemic symptoms. Gastrointestinal symptoms such as sensory allergy, nausea, vomiting, abdominal pain, poor appetite, diarrhea and constipation may be present. The face and conjunctiva are congested, and the skin of the neck and upper chest is flushed. Relatively slow pulse may be present during the febrile period. (2) The rash appears 2 to 5 days after the onset of fever, initially on the palms, soles of the feet or trunk and abdomen, gradually extending to the neck and extremities, and in some patients on the face, and may be maculopapular rash, measles-like rash, scarlet fever-like rash, erythematous rash, slightly prickly. Brown spots, which usually subside at the same time as the body temperature. (3) Bleeding occurs 5 to 8 days after the onset of the disease. (4) Lymph node enlargement The lymph nodes of the whole body may be mildly enlarged with light tenderness. (5) Other hepatomegaly may be present. Patients often feel weak after the disease and full recovery often takes several weeks. In severe dengue fever, headache, nausea, vomiting, impaired consciousness, meningoencephalitis, or in some cases, gastrointestinal hemorrhage and hemorrhagic shock appear on the 3rd to 5th day of the disease. This type often dies due to central respiratory failure and hemorrhagic shock because of the rapid development of the disease. 2, dengue hemorrhagic fever (1) shock generally occurs on the 2nd to 5th day of the course of the disease, lasting 12 to 24 hours, the patient is irritable, the limbs are cold, pale, the skin appears patterned, the body temperature drops, breathing is fast and irregular, the pulse is weak, the pulse pressure is progressively reduced, the blood pressure drops or even cannot be measured, the course of the disease can also appear cerebral edema, occasionally coma. If not rescued in time, death can occur in 4 to 10 hours. (2) Bleeding bleeding tendency is serious, with nasal bleeding, blood mass bruises on the skin, vomiting blood, blood in stool, hemoptysis, hematuria, vaginal bleeding and even intracranial bleeding. The 2014 dengue fever epidemic in Guangzhou refers to an outbreak of infected dengue fever cases in Guangzhou in June 2014, and this dengue fever epidemic Utah was particularly hard hit in Guangzhou. The epidemic then developed in various locations. As of October 6, 2014 the number of reported cases in the city has reached 19,631 cases, close to the 20,000 mark. 1,467 cases were added in Guangzhou on the 6th day. Guangzhou Health Bureau, the city’s CDC mosquito vector monitoring of the city’s 614 communities and villages found that only 259 met the standard, the rate of compliance is still not more than half.