Penis enlargement and thickening ointment medication is not real, and men should not apply it arbitrarily to avoid adverse consequences. Male penis development is mainly related to genetic factors, endocrine factors, disease factors, etc., whether it is a developing male or an adult male, can not be applied through the application of drugs or ointment to enlarge the penis. If such drugs are applied freely, adverse reactions such as local burning sensation, skin rash, nausea and vomiting may occur. For men with a short penis, there is no safe, effective way to improve the situation, patients can consider taking penile extension surgery and other ways of treatment, but there are certain risks associated with surgery, should be applied with caution. Men with short penises should not apply drugs for treatment, and should seek medical treatment as soon as possible and follow the doctor’s instructions for treatment.