Most snoring patients are accompanied by obesity, and the poor efficacy of upper airway surgery is mostly related to poor weight control of patients or further weight gain after surgery, and a foreign literature in 2014 showed that simple weight loss can lead to a decrease in OSAHS patients, while the current advocacy of exercise for weight loss is really slow, while the main thing is that most of them cannot be adhered to, I introduce several other methods below, hoping to be of Patients can help. Weight loss drugs: There are two major categories of weight loss drugs on the market today, pancreatic lipase inhibitors and appetite suppressants that act on the central nervous system. However, the latter still has safety uncertainties in the central brain and cardiovascular system, etc. So I will mainly introduce the former, currently the world’s only OTC (over-the-counter) is orlistat, there are a variety of trade names, look it up yourself. The mechanism is to lose weight by inhibiting pancreatic lipase activity, which in turn inhibits the breakdown and absorption of fat from food. Once the intake of calories and fats is less than the consumption, the body fat is naturally reduced, thus achieving the purpose of weight loss. It is safe for weight loss, the active ingredients do not enter the blood circulation and do not act on the central nervous system. The effect is definitely there, but there are also corresponding negative effects, mainly causing gastrointestinal adverse reactions, which are related to the pharmacological effect of the drug to prevent the absorption of ingested fat. Common adverse reactions are: oily spotting, increased gastrointestinal exhaustion, feeling of stool urgency, fatty (oily) stools, steatorrhea, increased stool frequency and fecal incontinence. Other rare adverse events are: upper respiratory tract infection, lower respiratory tract infection, influenza, headache, menstrual disorders, anxiety, fatigue, and urinary tract infection. Hypersensitivity to the product has been reported occasionally. The main clinical manifestations are pruritus, rash, urticaria, angioneurotic edema and allergic reactions, and the appearance of large herpes is very rare. Surgical surgery: this year at the National Sleep Congress in Qingdao (July 2015), a surgical weight loss group for obesity combined with OSAHS was established, indicating that the issue of surgery is also starting to be observed in China. 2014 a foreign meta-analysis article collected 12 corresponding articles and found that the average body mass index (BMI) of patients one year after surgery was reduced from 55.3 kg/m2 to 37.7 kg/ There is some efficacy. Currently there are laparoscopic adjustable gastric banding (LAGB), gastric sleeve resection (LSG), gastric bypass (LRYGB) and laparoscopic biliopancreatic obliteration and duodenal transposition (LBPD-DS). All are minimally invasive laparoscopic procedures. The main surgical modalities for obese patients with OSAHS in China are LSG and LRYGB, noting that there are too many morbidly obese people abroad for our countrymen to be so. That is why surgical outcomes are often reported to be better than abroad. As an ENT surgeon, although upper airway surgery is mostly used, as a sequential treatment of the disease, I hope that the majority of patients must pay attention to the issue of weight loss, which is a key factor to ensure the efficacy of surgery.