Drug allergy itchy skin can be dealt with through general treatment, medication and other ways. 1. General treatment: patients should avoid scratching the skin as much as possible to avoid infection after skin breakage. After finding out what kind of drug allergy should be discontinued in time, you can choose to reduce the dosage, stop under the guidance of a professional doctor to observe whether the itchy skin is relieved. 2. Drug treatment: If the general treatment effect is not good, you can also use anti-allergy drugs such as benzylamine, dexamethasone and so on to carry out anti-allergy treatment. It is best for patients to go to the hospital, complete the relevant examinations, such as routine blood tests, immune function, etc., so as to assess the condition. The above mentioned drugs should be taken under the guidance of a professional doctor, and should not be taken without authorization to avoid irreversible damage.