Prolactin is one of the six sex hormone tests. Elevated prolactin is called hyperprolactinemia, and it is associated with a variety of causes, most commonly pituitary factors. The cause of elevated prolactin first needs to be identified. Prolactin is secreted by the pituitary gland. The elevation may be related to pituitary tumors, hypothyroidism, etc. It is recommended to do relevant tests to clarify the cause and specific treatment. Currently, drug therapy is still the main treatment, supplemented by surgery and radiotherapy, and treatment is selected according to the principle of individualization. First of all, the secretion of lactogen should be inhibited, and the commonly used drug is bromocriptine mesylate. It can not only suppress the elevation of prolactin, but also control the growth of pituitary adenoma. Secondly, etiological treatment can be taken. In other words, different treatment methods can be used for the cause of elevated prolactin. For example, if hypothyroidism is the cause, thyroxine tablets should be supplemented appropriately based on the results of thyroid function tests. For drug-induced stress reactions, the drug can be discontinued for a period of time for observation. Patients with hyperprolactinemia who have fertility requirements can also be treated with bromocriptine first, and if ovulation still cannot be restored, combined treatment with ovulation-promoting drugs can be added. Patients with high prolactin who do not respond well to medication need to be further examined for pituitary tumor size and, if necessary, surgery may be required. Therefore, whenever elevated prolactin is found, the cause must be further investigated and treatment must be given.