In the 21st century, people liken depression to a “cold of the heart”, which is a common disease like cold and flu, and its incidence is extremely common. However, in the minds of many people, depression is not a disease at all, and is only regarded as a bad mood. In fact, depression is a disease that seriously jeopardizes human health, as are diabetes, coronary heart disease and hypertension. Just a few months, in our beautiful Yanjiang River, a young prison guard, a happy mom, a high-achieving child, a rich and powerful vice president committed suicide one after another …… The uncontrollable grief has awakened us once again: depression is all around us. Each of us must be concerned about depression; the mental pain is more difficult to bear than the physical. Nowadays, there are many people suffering from depression, and their life, study and work are greatly affected in all aspects. At present, there are more than 30 million people suffering from depression in China, and 15% of them eventually choose to commit suicide. We are all familiar with the role of “Huang Rong” Weng Meiling, writer San Mao, singer Ruan Lingyu, as well as the famous “brother” Zhang Guorong, and so on because of depression and suicide. Depression has become the second killer of human health among the global diseases, and the pain caused to patients and their families, as well as the loss to the society is incomparable to other diseases. Studies show that about one in 10 men and one in five women will suffer from depression at some point in their lives. Anyone, young or old, rich or poor, male or female, is at risk for depression. The WHO reports that by 2020 depression will be the second most disabling disease after cardiovascular disease. So what exactly is depression? Depression is a type of mental disorder caused by various reasons with low mood as the main symptom, it is a kind of high disease, high self-harm disease, also high recurrence, high death disease. The main manifestations of low mood, pessimism, disappointment, loss of energy, decreased interest, persistent fatigue, even if they do not do something, often feel fatigue, do not want to be active, slow thinking, lack of initiative, self-blame and self-guilt, feel sorry for the family, often accompanied by nervousness and restlessness, insomnia and early awakening, weight loss, worry about their own suffering from a variety of illnesses, and feel a lot of discomfort in many parts of the body, it is a chronic disease that affects the whole body, and the serious ones Often think of death, and even suicidal behavior, some patients will have hallucinations and delusions. Studies have shown that depressive disorder is the most common and important mental disorder most closely related to suicide, the vast majority of suicidal patients have the presence of depressive symptoms before death by suicide, of which about 60% or so of patients can be diagnosed as depression. So, how to catch the early signs of depression in time? Sleep disorders, especially difficulty in falling asleep and waking up early; physical discomfort but the doctor cannot check the specific cause. Patients often repeatedly consult neurology, gastroenterology and orthopedics because they feel obvious symptoms such as dull headache, chest tightness and breath holding, gastrointestinal discomfort and limb pain and weakness. I once saw a male patient in his 50s who said to me in tears, “Dr. Chen, please save me, I’ve seen every department except obstetrics and gynecology …… ; High mood swings. Emotional loss of control occurs, looking at everything, often getting angry over small things and regretting it later; slow reaction. Memory loss, slowness of movement, slow mental response, decreased work efficiency, etc. If you are unhappy mood and symptoms lingering, more than 2 weeks, and significantly affect the daily life and work, or suicidal thoughts, self-injurious behavior, it should be noted, consider whether you have depression, should seek professional consultation and treatment in a timely manner, depression is completely early recognition and can be cured disease.