Five effects Antispasmodic: relaxes bronchial smooth muscle and inhibits the release of allergic transmitters from allergic cells, while antispasmodic, it also reduces congestion and edema of bronchial mucosa; Cardiac: small doses can enhance the contraction of respiratory muscle and cardiac blood transfusion without accelerating the heart rate; dilates coronary arteries and peripheral blood vessels; Anti-inflammatory (small doses of valley concentration). Diuretic: increase renal blood flow and renal filtration rate with diuretic effect. Immunomodulatory effect. Five contraindications A contraindication to overdose. This drug has a central excitatory effect, can make a few patients insomnia and restlessness, too large a dose can occur convulsions, delirium. Second, avoid intravenous push or intravenous drip too fast. If the speed of this drug is too fast when pushing or dripping intravenously, the patient may appear agitation, convulsion, cardiac arrhythmia, blood pressure drop and other symptoms, and even cardiac and respiratory arrest. Therefore, aminophylline must be diluted and injected slowly. Thirdly, it is contraindicated to be used for those who are allergic to theophylline and its derivatives. Fourthly, it should not be given to children under 12 years old. Five contraindicated to use with ephedrine, caffeine, coramidine and other drugs. Five cautions Firstly, it should be used with caution in children who are particularly sensitive to the action of xanthine base. Second, with quinolones, enrofloxacin, ciprofloxacin, norfloxacin, pefloxacin will increase the blood concentration of aminophylline and the risk of aminophylline overdose should be cautious, because this may significantly reduce the metabolic effect of aminophylline and the risk of aminophylline overdose. Third, it should be used with caution in patients with cardiac, hepatic or coronary insufficiency, as well as in patients with hyperthyroidism, epilepsy, and obesity. Fourth, caution should be exercised when combining with macrolides (e.g. erythromycin, cross-actin, roxithromycin, etc.). Erythromycin can increase the concentration of aminophylline in the blood, and a dangerous overdose of aminophylline can occur. Fifth, caution should be exercised when combining with carbamazepine, phenobarbital, phenytoin sodium, rifabutin, rifampin, etc., cimetidine, fluconazole, mexiletine, hexaconitine, quinbendazole, ticlopidine, allopurinol, etc. These drugs may increase the blood concentration of aminophylline and pose a risk of toxicity.