Creatinine is a product of muscle metabolism in the body. Urinary creatinine mainly comes from the blood and is eliminated from the body with urine after filtration by the glomerulus, and is basically not absorbed by the renal tubules and is rarely excreted. It is mainly excreted from the body by glomerular filtration. Creatinine is also formed when meat is broken down in the body. Urinary creatinine levels in adult men range from 7 to 18 mmol/d; in women from 5.3 to 16 mmol/d. Urinary creatinine indicators have some reference value for the diagnosis of certain diseases. Increased urine creatinine can be seen in acromegaly, gigantism, diabetes, infection, hypothyroidism, eating too much meat, strenuous exercise, intake of certain drugs (such as vitamin C, levodopa, etc.). In life, we should prevent colds, control diet and emotions, do not strain, control blood pressure and blood sugar and other factors to protect kidney function. As long as you pay attention to these, urine creatinine will slowly come down. As mentioned above, urine creatinine mainly comes from the blood and is eliminated from the body with urine after filtration through the glomerulus. Adult male urine creatinine level is 7~18mmol/d; female is 5.3-16mmol/d. It has some reference value for the diagnosis of certain diseases.