Oral nifedipine extended-release tablets in the morning blood pressure can be, high blood pressure in the evening can be increased in the evening to take the drug once, need to comply with the doctor’s instructions to adjust the medication. Nifedipine extended-release tablets belong to the slow-release preparations, the action of the drug can last about 12 hours, most patients take once a day that can keep the daytime blood pressure stable, the nighttime blood pressure level is low, no need to take oral medication. For patients with high blood pressure at night, the drug can be taken once at night to ensure the effective concentration needed. Adverse reactions of nifedipine extended-release tablets include constipation, flushing, palpitations (rapid heartbeat, often accompanied by panic), edema of the lower limbs, etc. Long-term oral intake may lead to gingival hyperplasia, and it is contraindicated in patients who are allergic to the drug ingredients or have severe low blood pressure. Patients taking nifedipine extended-release tablets should pay attention to strengthen the monitoring of blood pressure, and oral drug therapy according to the characteristics of the drug’s action, the specific use of medication should be in accordance with medical advice.