Staphylococcus belongs to the genus Micrococcus, a genus of Gram-positive cocci in a grape-like arrangement, so it is given the name Staphylococcus. Among them, Staphylococcus aureus is a more important pathogenic bacteria, Staphylococcus aureus infections are mostly disseminated type. Staphylococcus aureus can cause an epidemic in large skin lesions, or in the neonatal ward of a burn unit. This is mainly because it is an important germ that causes septicemia and is very independent of Staphylococcus aureus. When penicillin was introduced, S. aureus was controlled to some extent, but with the widespread use of antibiotics, S. aureus became resistant to penicillin again, and more than 90% of S. aureus produce β-lactamase, which can hydrolyze the lactam ring of penicillin, so drug resistance occurs. However, in the course of future development, methicillin-resistant Staphylococcus aureus emerged, which is resistant not only to methicillin but also to other antibiotics. In short, while antibiotics continue to develop, this infectious bacterium continues to grow stronger. The most fundamental thing is not to abuse antibiotics in hospitals.