A piece of rough skin may be caused by physical friction, dermatophytosis, chronic eczema, chronic contact dermatitis, etc. The symptoms caused by various causes vary, and the skin abnormalities may be single or multiple and occur at different sites. 1. Physical friction: Physical friction of the skin locally for a long time may lead to roughness of the rubbed area without other abnormal signs. Patients should be careful to change the stress point at this time to avoid repeated rubbing of one area, and the skin may recover automatically after a period of time, generally without special treatment. 2. Dermatophytosis: When a patient has dermatophytosis, such as ringworm of the head, ringworm of the body, ringworm of the femur, ringworm of the hands, ringworm of the feet, etc., the lesioned skin appears as erythema, papules, and blisters, etc., and may flake with the development of the disease, resulting in rough skin. Depending on the strain of infection, you can choose bifenazole cream, ketoconazole cream, terbinafine cream, etc. to apply to the affected area to reduce the symptoms; 3. Chronic eczema, chronic contact dermatitis: Having chronic eczema, chronic contact dermatitis, etc., can lead to local skin hyperplasia, keratinization, hypertrophy, and even chapping of the patient due to the repeated stimulation of inflammation. It usually requires timely elimination of inflammation and removal of irritants to relieve skin abnormalities. If the skin becomes hard and rough, the cause should be determined based on the patient’s specific signs and professional examination results, and then targeted treatment should be performed.