Blood uric acid 600 μmol / L may be due to uric acid excretion obstacles and increased production. Patients can take febuxostat, allopurinol and other uric acid-lowering drugs as prescribed by the doctor for treatment. Blood uric acid of 600μmol/L is commonly caused by abnormal activity of enzymes that metabolize uric acid, decreased glomerular filtration rate and renal tubular dysfunction, leukemia, rhabdomyolysis and so on. Blood uric acid is 600μmol / L need to start uric acid lowering treatment, common uric acid lowering drugs for febuxostat, benzbromarone, probenecid, allopurinol, labrylase, etc., each kind of drug indications, contraindications and adverse effects of the drug are different. According to the patient’s specific condition, whether there are complications and other factors to develop individualized uric acid lowering drug treatment program, during the drug should be strictly abstaining from food, avoiding intake of high-purine diet, cardiac and renal function of the normal daily increase in the amount of drinking water to 1.5 ~ 2.0L, quit smoking, quit drinking, appropriate aerobic exercise. Drugs should be used under the guidance of a physician, it is recommended that patients who need to take uric acid-lowering drugs to the rheumatology and immunology departments of regular hospitals and other related departments to consult in detail after the prescribed medication.