With the opening of the two-child policy, many women over 35 years of age are now ready to get pregnant again, senior pregnancy for pregnant women and children have certain risks, how to smooth pregnancy and through the pregnancy and delivery period, to ensure the health of mother and child, need to do the following: 1, pre-conception preparation (1) three months before pregnancy to start taking folic acid tablets 0.4mg per day, if ever pregnant with neural tube malformation fetal, folic acid needs (2) physical examination The couple should have a full body physical examination: a comprehensive examination of the heart, liver, kidneys and other organs to find out whether there is hypertension, hyperlipidemia, diabetes, and if hypertension and diabetes are found, they should be consulted and treated at the corresponding specialist, who will decide whether they can get pregnant, control the blood pressure and blood sugar within a reasonable range, and use the drugs that can be used during pregnancy; those who have not done If you have not been screened for genetic diseases such as thalassemia, you need to do hemoglobin electrophoresis and G6PD test, and if necessary, thalassemia gene test to exclude thalassemia. Gynecological examination of the female partner: cervical cancer screening, vaginal discharge examination, ultrasound of uterine adnexa, ovarian function examination to exclude cervical cancer or precancerous lesions, vaginitis, and to understand the presence of uterine fibroids and ovarian tumors. For those over 40 years old, it is recommended to check AMH (anti-Mullerian duct antibodies) for a more accurate assessment of fertility. Male partner examination: In addition to the above mentioned blood tests, semen routine and morphological analysis should be done to check the sperm survival rate, motility rate, malformation rate and liquefaction rate, etc. If there is any problem, appropriate treatment is needed. Some men with varicocele need further treatment. Men should also be careful not to take saunas, go to hot springs, wear tight pants, or drive long distances. 2.Pregnancy (1) If you are taking medication for internal diseases before pregnancy, you should continue to take medication after pregnancy, and some of them need to change to medication available during pregnancy, and follow up regularly with the appropriate specialist; (2) Regular maternity checkups according to the regular maternity checkup process (refer to the article “Maternity Checkup Process”); (3) Interventional prenatal diagnosis in the middle of pregnancy: amniotic fluid chromosome examination by amniocentesis from 18 to 23 weeks, and cordocentesis can be done after 24 weeks (4) monitoring blood pressure and blood glucose in the middle and late pregnancy: gestational hypertension and gestational diabetes are likely to occur in advanced pregnancies, so you should pay attention to rest, control salt intake, supplement calcium, iron and folic acid, achieve a balanced diet, high protein, high vitamin, low sugar and low fat diet, and absolutely avoid smoking and alcoholic beverages. If gestational diabetes is diagnosed, blood glucose must be controlled strictly through diet control, with insulin if necessary; once dizziness, blurred eyes, and lower limb edema occur, blood pressure must be measured, and if it exceeds 140/90 mmHg, seek medical attention as soon as possible and check urine routine for proteinuria. If necessary, hospitalize for monitoring and treatment. (5) Weight control: As age increases, body metabolism slows down and advanced maternal age is more likely to be obese. Both giant babies and maternal obesity increase the rate of cesarean delivery and difficult delivery. It is important to control weight in the middle and late pregnancy, gaining no more than 500g per week, and pregnant women with diabetes need to monitor various physical data more closely. 3.Delivery period As long as there are no pregnancy complications or obstetric complications, advanced age is not an indication for cesarean delivery. Mode of delivery: If the first child is delivered by normal delivery, the second child should be delivered vaginally as far as possible; if the first child is delivered by cesarean section, the second child should be delivered by referring to the article “Can scarred uterus be delivered by normal delivery? The second child should be delivered vaginally as much as possible; if the first child is delivered by cesarean section, the second child should be delivered by referring to the article “Can scarred uterus be delivered by normal delivery? 4, breastfeeding As in the case of low-age pregnant women, breastfeeding should be encouraged for about one year after delivery; routine check-ups should be conducted 42 days after delivery to understand the recovery of the uterus; for women who have experienced two vaginal deliveries, there will be varying degrees of vaginal laxity and bladder bulge, and pelvic floor rehabilitation should be carried out to avoid urine leakage, which will affect the quality of life in the future.