Trigeminal neuralgia is episodic pain, each attack lasts for a number of seconds or minutes, intermittent painless or only mild dull pain, there may be trigger points or trigger bands on the face, the pain is confined to one side of the trigeminal nerve area and does not exceed the midline, there is usually no hyperalgesia or hypersensitivity. 1.Medication is the main treatment for trigeminal neuralgia. (1) Carbamazepine: This drug can relieve pain in 2/3 of patients. Start with 100mg per day, increase 100mg every other day until 600mg/d, maintain this dose for 1 week, if the pain is not relieved, it can be increased to 800mg/d, the maximum dose is 1.2-1.6g/d, then increase the dose effect no longer increase. After the pain stops, adjust the dose downward to maintain. The side effects include gastrointestinal irritation, ataxia, dizziness, drowsiness, bone marrow suppression and abnormal liver function. (2) Phenytoin sodium: It is the second-line drug for the treatment of trigeminal neuralgia. The initial application is 200mg twice a day, and the effective blood concentration (15-25mg/ml) can be achieved by gradually increasing to 300-400mg within 3 weeks. Side effects include nystagmus, ataxia, leukopenia, abnormal liver function, osteoporosis, etc. (3) Other drugs: Baclofen is a relatively new drug, with a starting dose of 5mg/d, increasing by 5mg every two days until pain relief or toxic reactions occur, with a maximum dose of 80mg/d, which is gradually reduced after pain relief. 2. Nerve block: The corresponding nerve block should be used according to the area where the pain is distributed. Branch I: supraorbital nerve block and supracarinal nerve block; Branch II: infraorbital nerve block and maxillary nerve block; Branch III: chin nerve block, inferior alveolar nerve block and mandibular nerve block. For patients with short history and mild symptoms, repeated blocks with local anesthetics can be used; while those with long history or severe symptoms should be switched to nerve-destroying drugs. 3, radiofrequency therapy: radiofrequency thermal coagulation can adjust the temperature to control the scope and degree of destruction, generally 50 ° C can produce a heavy sensory hyperalgesia, 70 ° C pain disappears. Short-term efficacy of more than 90%, but the long-term effect is not ideal, recurrence rate of 6-53%, can produce keratitis, loss of corneal reflex, abnormal sensation and other complications. 4.Surgical treatment: if the persistent trigeminal neuralgia, medication and the above treatment methods are ineffective, or there are intolerable side effects, surgical treatment can be considered.