Pharmacological treatments for premature ejaculation mainly include selective 5-HT reuptake inhibitors and topical local anesthetics. The specific use of drugs to go to consult the doctor. 1. 5-HT reuptake inhibitors now the main drug for dapoxetine, such drugs can increase the concentration of 5-HT in the body. Studies have shown that 5-HT receptors play a key role in the control of ejaculation. Contraindications include stroke and heart attack, low blood pressure, previous history of severe cardiovascular disease, and patients with severe liver damage. 2. Local anesthesia drugs mainly include lidocaine aerosol, etc., the use of which is sprayed on the glans locally, thus prolonging the patient’s ejaculatory latency. Contraindications include severe hepatic and renal dysfunction. It is contraindicated in those with abnormal hepatic blood flow, heart failure, and myocardial damage. Once you notice similar symptoms of premature ejaculation, seek medical attention. The medication is administered under the guidance of a doctor.