I had a patient who had a lot of questions about pregnancy. I have not encountered this problem much and have collected some information summarized below. During pregnancy, due to fluctuations in hormone levels and some changes in autoimmunity, some patients may have exacerbations, some patients have no significant changes in their disease, and some patients have reductions in their disease. The proportion of patients in these three categories is reported differently in different articles, with some reports stating that each accounts for one third. Regarding the mode of delivery, since the skeletal muscles, such as the abdominal muscles, are needed to assist in the delivery process, some patients will experience muscle fatigue and weakness, and the proportion of cesarean delivery increases, but some patients with mild disease and good conditions with the possibility of a smooth delivery can also be considered for a normal delivery, although the decision should be made carefully and discussed fully with obstetricians and neurologists. General anesthesia should not be chosen for cesarean section as much as possible. Glucocorticoids such as prednisone may have some effects on the fetus, such as increasing the incidence of cleft lip and cleft palate, but they are relatively rare and are generally considered acceptable. And if previously taking immunosuppressants (non-hormonal), they should also be converted to hormones to control symptoms smoothly before pregnancy. Immunosuppressants such as azathioprine, cyclosporine, and tacrolimus are generally considered to have strong teratogenic effects and should be avoided (the instructions for these drugs generally emphasize avoidance during pregnancy). The application of a range of drugs that may aggravate the condition during pregnancy should be even more important. In particular, the application of magnesium sulfate should be avoided in cases of pre-eclampsia and eclampsia, as it may aggravate the myasthenia gravis condition. Due to the limitations of medication use during pregnancy, it is generally recommended to surgically remove the thymus gland before pregnancy to reduce the use of medication during pregnancy. Since thymectomy is most effective when performed within one year of the onset of the disease and may take about three years to reach maximum efficacy, the timing of thymectomy and pregnancy should be planned. Transient myasthenia gravis occurs in about 10-20% of infants and may last for several weeks, with reduced intrauterine activity in individual fetuses and even joint contractures in some, but these occur at a very low rate. Symptoms of neonatal myasthenia gravis are generally thought to be due to antibodies from the mother’s body reaching the fetus through the placenta, so the symptoms usually resolve when the antibodies are metabolized in the first few weeks after birth. The above fetal and infant abnormalities should be guarded against. For the treatment of neonatal myasthenia gravis, the first step should be early detection, timely supportive treatment, maintenance of respiration, nutrition and other general conditions, and drug treatment can be applied to bromipyridamole.