In the past two years, the Department of Cardiac Surgery has successfully treated 30 patients with critical “large aneurysms”. “Large aneurysms” include aortic aneurysms, aortic coarctation and entrapment aneurysms. The treatment methods used include open surgery, minimally invasive interventional repair, and “hybrid” technology, which cover the three most advanced methods for treating “large artery aneurysms” at home and abroad. To perform these procedures, multidisciplinary collaboration is required, including cardiac surgery, extracorporeal circulation, anesthesiology, operating room, interventional radiology, intensive care, and diagnostic ultrasound. The series of therapeutic options for “large aneurysms”: open thoracic, interventional and Hybrid techniques, represent the most advanced and innovative techniques in the field of cardiovascular surgery. Each of the three techniques has its own advantages and disadvantages. Open-heart surgery is characterized by high trauma and complications, but it can resolve almost all types of aortic aneurysms/aortic coarctation. Interventional therapy refers to “minimally invasive endoluminal repair”, which is very traumatic, and has reduced the mortality rate of surgery to about 5%, and the paraplegia rate from 25% to 0.8%, which significantly improves the safety and efficacy of the treatment; however, interventional therapy can only solve some types of aortic aneurysm/aortic coarctation. For those complex aortic diseases that cannot be treated satisfactorily with simple surgical or interventional treatments, the application of Hybrid technology can effectively expand the indications for surgery and enable surgical cures for some previously untreatable or difficult-to-treat cases. Unlike most hospitals, the Department of Cardiothoracic Surgery is equipped with the three techniques of open-heart, interventional, and hybrid, which, together with our multidisciplinary cooperation, can often provide the most appropriate treatment for patients with aortic aneurysm/aortic coarctation and achieve the best therapeutic results. The complementary application of open thoracic, interventional, and Hybrid techniques can make up for the deficiencies of single surgical or single interventional treatments, reduce the trauma and risk of multiple surgeries, and provide patients with the optimal treatment, thus comprehensively improving the clinical treatment of macrovascular diseases. These 30 patients with critical aortic aneurysm/aortic coarctation had no complications and were discharged from the hospital with good follow-up. “The full implementation of open thoracic, interventional, and hybrid techniques for aortic aneurysms in our hospital represents a milestone in the development of aortic surgery in our hospital.