Chest tightness, dizziness and nausea are explained with a monistic view, mostly occurring among patients with heart disease, as follows: 1. Heart disease is a collective term for a variety of diseases, including congenital heart disease and acquired heart disease, and heart disease can present a variety of states, including the state of myocardial ischemia, which can present angina pectoris and myocardial infarction, which can manifest as chest tightness, chest pain, palpitations, and abnormal shortness of breath; 2. Heart disease can cause hypoperfusion of peripheral target organs, resulting in symptoms such as dizziness, headache, reduced exercise, and weakness; 3. Heart disease that causes stasis in the body circulation can cause symptoms related to gastrointestinal stasis, such as abdominal pain, abdominal distension, nausea, and vomiting. Therefore, for chest tightness, dizziness and nausea, the monism is used to explain the consideration of heart disease, but it needs to be distinguished from other systemic diseases, including physical and chemical factors, poisoning, etc., which can also cause the occurrence of chest tightness, dizziness and nausea symptoms.