For women with irregular menstruation, taking hormone pills may lead to gastrointestinal discomfort, breast swelling and pain, thrombosis, liver and kidney function damage and other adverse effects. 1. Gastrointestinal discomfort: for women with fragile gastrointestinal function, taking the drug may cause nausea, vomiting and other discomforts, so it is generally recommended that patients take the drug after meals. 2. Breast swelling and pain: Because of the distribution of estrogen receptors in the breasts, patients may experience breast swelling and pain when taking estrogen-containing drugs, and the symptoms can be relieved after stopping the drugs. 3. Thrombosis: Since estrogen will lead to an increase in blood viscosity, which in turn affects blood flow, thus increasing the risk of thrombosis. 4. Impairment of liver and kidney function: Since estrogen and progesterone will be metabolized by the liver and kidneys, if too much is consumed, it may increase the burden on the liver and kidneys, which may lead to the elevation of aminotransferases, creatinine, and other test indicators. For women with irregular menstruation, if they need to use hormone therapy, it is recommended that they take supplements under the guidance of a doctor and should not use drugs blindly.