Lenvatinib belongs to the anti-tumor targeted drugs, will affect the coagulation function, there will be bleeding adverse reactions, if bleeding occurs, you can suspend the administration of the drug, adjust the dosage or stop the drug, if the bleeding adverse reactions of grade 3, you need to suspend the Lenvatinib medication, to be relieved to grade 0-1 and then resume or reduce the amount of Lenvatinib antitumor therapy; if the bleeding adverse reactions of grade 4, you need to permanently stop the Lenvatinib antitumor therapy. For gum bleeding, first of all, should check poor oral hygiene, periodontal calculus, can lead to gingivitis, these may also lead to gum bleeding, lenvatinib should be regularly rechecked during the period of administration of coagulation function, blood routine and other tests, if necessary, can be symptomatic treatment of oral antiemetic drugs. Patients with bleeding gums during the medication period should consult a doctor in time and follow the professional doctor’s advice and suggestions before deciding on the next step of treatment.