Breast cancer treatment without missing breast With the rapid development of breast cancer treatment technology, the rate of disease-free survival of breast cancer patients after surgery has been further improved, so the focus on quality of life after surgery has become an important part of modern medical treatment. While scientifically increasing the proportion of breast-conserving surgery for breast cancer, some patients who have lost the chance of breast-conserving surgery are treated with total mastectomy and immediate breast reconstruction, so as to enter the era of breast cancer treatment without breast loss. The percentage of breast-conserving surgery for breast cancer in our oncology center exceeds 50%, and in recent years, we have carried out immediate breast reconstruction surgery for radical breast cancer, which fundamentally improves the quality of life of patients after surgery. Since 2001, the breast magnetic resonance technology has been carried out with the radiology department of our hospital in Beijing, which can accurately determine the size of breast cancer and the distance of infiltration in the surrounding breast ducts, so as to select the surgical method more scientifically and determine the smallest effective resection area for surgery, avoiding blind oversized resection. This reduces the uncertainty of additional excision in case of residual margins, thus reducing the possibility of local recurrence after surgery. The option of breast-conserving surgery was abandoned for cases with extensive intraductal infiltration and multicentric breast cancer as demonstrated by magnetic resonance. Breast cancer surgery has evolved from the treatment concept of maximum tolerable resection to minimum effective resection. Breast-conserving surgery is undoubtedly a more desirable surgical option for breast cancer patients who meet the indications for breast conservation, but some patients still have to undergo total mastectomy for larger tumors, extensive infiltration and multicentric breast cancer, or due to some subjective factors of the patient. Breast reconstruction can fundamentally improve the quality of life of these patients after surgery and solve the problems of body asymmetry and breast constriction, especially immediate reconstruction has more advantages: it avoids the malignant stimulation generated by breast loss in visual and psychological aspects as well as the trauma and cost of second-stage surgery and anesthesia, and minimizes the psychological trauma brought by breast loss to patients. It is now believed that stage I and II breast cancer are indications for immediate breast reconstruction, and now some stage III and IV breast cancers are not absolute contraindications. Several studies have ruled out the fear that breast reconstruction surgery will affect tumor prognosis, and long-term follow-up results show that immediate breast reconstruction surgery does not increase the risk of local recurrence and distant metastasis. Immediate reconstructive breast surgery is a safe and feasible surgical treatment for patients with locally advanced breast cancer, and immediate myocutaneous flap breast reconstruction does not increase complications and can be successfully treated with adjuvant chemotherapy and radiotherapy. In recent years, our oncology center has carried out immediate breast reconstruction with modified radical breast cancer, and only one case had flap edge necrosis and delayed healing. Immediate breast reconstruction includes: breast reconstruction with rectus abdominis flap, breast reconstruction with latissimus dorsi flap, breast reconstruction with implantation of total subcutaneous breast implant with preserved nipple-areola complex, breast reconstruction with implantation of total subcutaneous breast implant with latissimus dorsi flap with preserved nipple-areola complex, in which there are many cases of locally advanced breast cancer (including cases with extensive recurrence in the chest wall after radical surgery). In many of these cases, due to the extensive infiltration, it was difficult to perform conventional surgery, and simple wound implantation would have a great impact on the appearance and morphology, and would be poorly tolerated by postoperative radiotherapy, and would even result in more severe radiation ulcers. Therefore, we use myocutaneous flap breast reconstruction to solve the larger defect coverage and ensure adequate excisional coverage, and there are no local recurrence cases in follow-up to date. We advocate scientific breast-conserving treatment for breast cancer combined with immediate breast reconstruction for radical breast cancer, and move into the era of breast cancer treatment without breast defects, so that more breast patients can obtain a higher quality of life after surgery while ensuring radical treatment.